Regeneration of neuronal cell types in Schmidtea mediterranea: an immunohistochemical and expression study
نویسندگان
چکیده
منابع مشابه
Regeneration of neuronal cell types in Schmidtea mediterranea: an immunohistochemical and expression study.
Freshwater planarians are unique in their ability to regenerate a complete Central Nervous System (CNS) from almost any small piece of their body in just a few days. The planarian CNS contains a pair of anterior cephalic ganglia lying on top of two ventral nerve cords that extend along the length of the animal. Studies of planarian CNS regeneration have generally used pan-neural markers, which ...
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Planarians can regenerate any missing body part in a process requiring dividing cells called neoblasts. Historically, neoblasts have largely been considered a homogeneous stem cell population. Most studies, however, analyzed neoblasts at the population rather than the single-cell level, leaving the degree of heterogeneity in this population unresolved. We combined RNA sequencing of neoblasts fr...
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Planarians have been used as a model to study development and regeneration for more than 200 years. Research on these animals has traditionally focused on surgical and pharmacological manipulations. Recently, the dissection of planarians has become more molecular in nature. The isolation of thousands of expressed sequence tags and the introduction of in situ hybridizations, immunocytology, and ...
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ژورنال
عنوان ژورنال: The International Journal of Developmental Biology
سال: 2012
ISSN: 0214-6282
DOI: 10.1387/ijdb.113428sf